Infectious diseases — Table I
Officially | Officially | Officially | Officially |
| Recent studies from 2019 have estimated that the prevalence of chronic HCV has declined, but could still be as high as 2.86%. The data indicates that the prevalence of chronic Hepatitis C (HCV) infection among the surveyed population in 2022 was 2.12%. 1 | The total number of HIV cases registered by 31.12.2020 amounts at 13,706, of these persons 9,407 are alive and know their status. During the reporting period AIDS was confirmed in 286 cases, including 45 cases on the Left Border (in 2018 – 364 and 72, respectively). Of these, in 168 cases (58.74%) AIDS disease was confirmed in persons diagnosed with HIV in 2019.2 | HIV prevalence in general population is 0.3% (0.24% for the left border and 0.62% for the right one). The Republic of Moldova is one of 30 countries with high burden of MDR-TB. In 2019, estimated incidence rate for TB was 80 per 100 000 population and the mortality rate was 6.3 per 100,000 population [1]. In 2019, 2,809 TB cases were notified. It is also estimated that 33% of new cases and 60% of previously treated cases were MDR/RR-TB.3 | In 2022, 929 new cases of HIV were registered among residents of Moldova. The total number of people living with HIV, according to UNAIDS estimates, exceeded 16,000, while only 10,000 were officially registered in the healthcare system.)4 |
HIV situation
In Moldova, the HIV epidemic remains concentrated in key populations, including people who inject drugs (PWID), sex workers (SW), and men who have sex with men (MSM). The estimated HIV prevalence is about 0.3% in the general population, but it is much higher within these groups. Over recent years, transmission trends have shifted, with an increase in cases resulting from sexual transmission rather than injection drug use alone. This change reflects an evolution from an early concentrated epidemic to a more advanced concentrated epidemic where transmission is occurring from key populations to their sexual partners.
Regions like Chisinau and Balti, Moldova’s most affected cities, have implemented enhanced HIV response efforts since joining the Paris Declaration in 2019. Despite these efforts, access to testing, treatment, and harm reduction services still faces barriers, especially in the Transnistrian region. Moldova’s response includes support from the Global Fund, which funds harm reduction and first-line treatment initiatives, contributing to coverage for approximately 4,500 key population members and 1,500 patients in Transnistria.
Efforts continue to adapt strategies, aiming to improve accessibility, reduce stigma, and expand coverage to curb new infections and support Moldova’s commitment to ending the AIDS epidemic by 2030.

